What is itachis illness

We dont know if hus internal organs or chakra flow ever fully recovered after that,and the tremendous strain from using mangekyo and other techniques was probably a bit too much with a deficient chakra flow.

Every time he used chakra probably affected his vital organs somehow. This seems unlikely,simce i cant see him being unable to be treated, since hinata was able to recover after neji tried to kill her,but its the best theory i have.

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Active 2 years, 7 months ago. Viewed 21k times. Improve this question. Anonymous Anonymous 2 2 gold badges 2 2 silver badges 3 3 bronze badges. One could probably even argue his thin stature is evidence of weight loss. There are, of course, come classic manifestations of MPA that cannot be observed in Itachi.

This, however, dos not mean that they can't be rectified. One of the most common ways MPA manifests itself is with renal involvement.

We have no evidence that Itachi's kidneys have been damaged by disease. However, it is possible the damage is there, and simply did not produce outward, observable symptoms. At least half the cases of MPA also report skin involvement. This can range from small blisters to necrosis and gangrene. There are reports, however, of MPA only causing splinter hemorrhages, or small areas of bleeding under the nails.

As the Akatsuki always wear nail polish, this would be completely unobservable. Long story short, the symptoms fit. In fact, they're pretty much textbook. Next, we consider what we know about how the disease was managed. Madara describes Itachi's disease to Sasuke in one panel.

There, he reveals that Itachi took a variety of different medicines to keep himself alive. He could easily be describing the treatment of MPA, which requires a combination of different steroids and immunosuppressive agents. Because treating the disease requires suppressing his immune system, Itachi likely needed other drugs as well, including specific types of antibiotics and vitamins.

Tobi mentioned that Itachi was sick with a disease, and was taking medicine for it to extend his life. Like the first and single answer said in this question, Itachi died of hymoptesis while fighting Sasuke Uchiha. Itachi got this illness when he used his Mangekyou Sharingan too much. He was very good at analysing the skills of the opponents. The opponents Like Madra and Jigen praises his analysing skills.

Many opponents consider him a greater threat than Naruto. A lot of the reasons why people dislike Sasuke is down to a misunderstanding of how he was written.

However, the later clarification of his illness causing impending doom implies its unrelated to jutsu. Itachi died easily because he allowed Sasuke to defeat him. Some reputation was restored to the Uchiha clan. Itachi has fought, killed, or escaped from dozens of high ranking and notorious ninja.